Long-term renal outcomes and mortality following renal injury among myocardial infarction patients treated by primary percutaneous intervention
Long-term renal outcomes and mortality following renal injury among myocardial infarction patients treated by primary percutaneous intervention
复制标题
DOI：
10.1097/mca.0000000000000678
复制
发表时间：
2019-03-01
影响因子：
1.8
通讯作者：
Shacham, Yacov
中科院分区：
文献类型：
--
作者：
Kofman, Natalia;Margolis, Gilad;Shacham, Yacov
目的：ST段抬高型心肌梗死（STEMI）患者行直接经皮冠状动脉介入治疗（PCI）后急性肾损伤（阿基）后持续性肾损害的数据有限。我们评估了急性肾脏疾病（AKD）的发病率和预后影响，定义为肾功能下降的持续时间为7至90天之间的暴露后，阿基引发的事件，以及长期的肾结果STEMI患者接受直接PCI谁开发阿基.Patients和方法，我们回顾性研究了225个连续STEMI患者谁开发阿基。根据在出院后7天和肾损伤后90-180天内测量的血清肌酐水平，评估患者AKD的发生率和长期肾脏结局。结果81/225例（36%）患者进展为AKD，且90天内进展为AKD的患者死亡率较高（35 vs. 11%，P
Objectives Limited data are present on persistent renal impairment following acute kidney injury (AKI) among ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). We evaluated the incidence and prognostic implications of acute kidney disease (AKD), defined as reduced kidney function for the duration of between 7 and 90 days after exposure to an AKI initiating event, as well as long-term renal outcomes among STEMI patients undergoing primary PCI who developed AKI.Patients and methods We retrospectively studied 225 consecutive STEMI patients who developed AKI. Patients were assessed for the occurrence of AKD and long-term renal outcomes on the basis of serum creatinine levels measured at 7 days/hospital discharge and within 90-180 days of renal insult. Mortality was assessed at 90 days and over a period of 1271 +/- 903 days (range: 2-2130 days) following the renal insult.Results Progression to AKD occurred in 81/225 (36%) patients and was associated with higher 90-day (35 vs. 11%, P