Cell-size control: Chromatin-based titration primes inhibitor dilution.
Cell-size control: Chromatin-based titration primes inhibitor dilution.
复制标题
细胞大小控制：基于染色质的滴定引发抑制剂稀释。
DOI：
10.1016/j.cub.2021.08.031
复制
发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Skotheim,JanM
中科院分区：
文献类型：
--
作者：
Xie,Shicong;Skotheim,JanM
细胞生长可以通过稀释酵母、动物和植物细胞中的多种细胞周期抑制剂来推动进入细胞周期。当大细胞和小细胞继承相似数量的抑制剂分子时，抑制剂稀释机制实现细胞大小控制，新的研究表明植物细胞中的这些机制包括特定的降解和染色质分配成分。
Cell growth can drive progression into the cell cycle by diluting a diverse set of cell-cycle inhibitors in yeast, animal, and plant cells. Inhibitor dilution mechanisms implement cell-size control when large and small cells inherit a similar number of inhibitor molecules, and new work shows that these mechanisms in plant cells include specific degradation and chromatin-partitioning components.