Multi-metal interactions between Cd, Cu, Ni, Pb and Zn in water flea Daphnia magna, a stable isotope experiment
Multi-metal interactions between Cd, Cu, Ni, Pb and Zn in water flea Daphnia magna, a stable isotope experiment
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DOI：
10.1016/j.aquatox.2008.08.007
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发表时间：
2008-11-11
影响因子：
4.5
通讯作者：
Blust, R.
中科院分区：
文献类型：
--
作者：
Komjarova, I.;Blust, R.
金属相互作用的影响，大型蚤在同时暴露于必需的（铜，镍和锌）和非必需的（镉和铅）金属在环境相关的浓度，使用稳定同位素技术。金属的施用浓度范围如下：Cd-106为0.0125-0.2 μ M，Cu-65和Pb-204为0.025-0.25 μ M，Ni-62和Zn-67为0.1-1.25 μ M。镉和铜表现出抑制作用的所有其他金属的吸收率存在于混合物中的例外，铅在所有研究的浓度。在低浓度的镉和铜的效果已经很明显，并达到最大值在较高的浓度。镍和锌与镉的相互作用和相互作用较弱，而对铜和铅的吸收没有影响。镉，镍和锌的吸收率之间有很高的相关性，这表明这些金属共享部分共同的吸收或相互作用的途径。此外，锌和铜的吸收过程之间的显着相关性表明，一个以上的机制参与锌的积累，因为铜是已知的相互作用与钠的吸收网站。铅的吸收具有较高的初始速率，但在24 h内达到饱和。镉施加在0.2 μ M的浓度是唯一的金属，影响铅吸收过程中的铅吸收的刺激。添加到介质中的浓度为0.25 μ M，铅反过来，增加铜的吸收。目前的工作表明，金属的相互作用是显着的，发生在低环境现实浓度影响有毒和必需金属的生物利用度。(c)2008 Elsevier B. V.保留所有权利。
Metal interaction effects were investigated in Daphnia magna during a simultaneous exposure to essential (Cu, Ni and Zn) and non-essential (Cd and Pb) metals at environmentally relevant concentrations using a stable isotope technique. The metals were applied in the following concentration ranges: 0.0125-0.2 mu M for Cd-106, 0.025-0.25 mu M for Cu-65 and Pb-204, 0.1-1.25 mu M for Ni-62 and Zn-67. Cadmium and copper exhibited a suppressing effect on the uptake rates of all other metals present in the mixture with the exception to lead at all studied concentrations. The effect was already pronounced at low Cd and Cu concentrations and reached a maximum at the higher concentrations. Nickel and zinc showed weaker interactions with cadmium and between each other, while having no effect on copper and lead uptake. There was a high degree of correlation between Cd, Ni and Zn uptake rates indicating that these metals share in part common uptake or interaction pathways. Moreover, a significant correlation between Zn and Cu uptake processes suggests that more than one mechanism is involved in Zn accumulation since Cu is known to interact with Na uptake sites. The uptake of lead was marked by a high initial rate, but the uptake process reached saturation within 24 h. Cd applied at a concentration of 0.2 mu M was the only metal which affected the lead uptake process by stimulation of the Pb uptake. Added to the medium at a concentration of 0.25 mu M, lead in turn, increased copper uptake. Current work illustrates that metal interactions are significant and occur at low environmentally realistic concentrations affecting bioavailability of both toxic and essential metals. (c) 2008 Elsevier B.V. All rights reserved.