The time course of binocular rivalry during the phases of the menstrual cycle.
The time course of binocular rivalry during the phases of the menstrual cycle.
复制标题
月经周期各阶段双眼竞争的时间过程。
DOI：
10.1167/16.15.22
复制
发表时间：
2016
影响因子：
1.8
通讯作者：
Blake,Randolph
中科院分区：
文献类型：
--
作者：
Sy,JocelynL;Tomarken,AndrewJ;Patel,Vaama;Blake,Randolph
当两只眼睛的明显不同的输入引发两只眼睛的视图之间的知觉优势交替时，就会发生双眼竞争。竞争感知动态的个体差异与 GABA（大脑中一种重要的抑制性神经递质）浓度之间的联系，凸显了双眼竞争作为研究大脑抑制过程的潜在工具。本实验调查了先前报道的健康月经周期中 GABA 浓度的波动（Epperson 等，2002）是否也与个体内部竞争动态的可测量变化相关。我们在 5 周内对健康女性参与者进行了 300 个竞争跟踪块的测量，获得了交替率、优势和混合持续时间的纵向测量结果，这些参与者监测了其周期中卵泡和黄体阶段的开始。尽管我们在竞争动态中证明了强大而稳定的个体差异，但通过分析方法和依赖性测量，我们发现在月经阶段的主导知觉的时间动态中没有显着的变化甚至趋势。当跨会话和块汇集数据时，我们发现混合感知的偏斜和峰度仅存在稀疏的阶段间差异。这些结果表明，激素类固醇、双眼竞争和大脑中的 GABAeric 信号之间存在复杂的动态关系，因此暗示在将 GABA 与双眼竞争中的知觉变化联系起来时需要考虑系统视角。
Binocular rivalry occurs when markedly different inputs to the two eyes initiate alternations in perceptual dominance between the two eyes' views. A link between individual differences in perceptual dynamics of rivalry and concentrations of GABA, a prominent inhibitory neurotransmitter in the brain, has highlighted binocular rivalry as a potential tool to investigate inhibitory processes in the brain. The present experiment investigated whether previously reported fluctuations of GABA concentrations in a healthy menstrual cycle (Epperson et al., 2002) also are associated with measurable changes in rivalry dynamics within individuals. We obtained longitudinal measures of alternation rate, dominance, and mixture durations in 300 rivalry tracking blocks measured over 5 weeks from healthy female participants who monitored the start of the follicular and luteal phases of their cycle. Although we demonstrate robust and stable individual differences in rivalry dynamics, across analytic approaches and dependent measures, we found no significant change or even trends across menstrual phases in the temporal dynamics of dominance percepts. We found only sparse between-phase differences in skew and kurtosis on mixture percepts when data were pooled across sessions and blocks. These results suggest a complex dynamic between hormonal steroids, binocular rivalry, and GABAeric signaling in the brain and thus implicate the need to consider a systemic perspective when linking GABA with perceptual alternations in binocular rivalry.