Biological effects of static magnetic fields on the microcirculatory blood flow in vivo: a preliminary report

Biological effects of static magnetic fields on the microcirculatory blood flow in vivo: a preliminary report
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DOI:
10.1007/bf02522863
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发表时间:
1998-01-01
影响因子:
3.2
通讯作者:
Ueno, S
Ueno, S
中科院分区:
工程技术3区
文献类型:
--
作者:
Ichioka, S;Iwasaka, M;Ueno, S

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目前关于静磁场对体内微循环血流动力学影响的研究较少。采用大鼠皮肤折叠透明腔技术,为观察和定量体内微血管在高达8 t静磁场下的直接血流动力学反应提供了一种极好的方法。采用活体视频显微镜测量了在直径为100 mm、长为700 mm的水平超导磁体中暴露磁场20 min前后的血流变化。暴露后,微循环血流量开始增加约5分钟,随后逐渐减少并恢复到控制值。据推测,这些变化代表暴露期间血流量减少后的反弹性充血。
There have been few studies of the effect of static magnetic fields on microcirculatory haemodynamics in vivo. The rat skinfold transparent chamber technique was used, which provides an excellent means of observing and quantifying direct in vivo microvascular haemodynamic responses to static magnetic fields up to 8 T. An intravital videomicroscope was used to measure the changes in blood flow before and after exposure to a magnetic field for 20 min in a horizontal type superconducting magnet with a bore 100 mm in diameter and 700 mm long. After exposure, microcirculatory blood flow showed an initial increase for about 5 min followed by a gradual decrease and a return to the control value. It is hypothesised that these changes represent rebound hyperaemia following reduced blood flow during exposure.