Effects of Dietary Protein and Fiber at Breakfast on Appetite, ad Libitum Energy Intake at Lunch, and Neural Responses to Visual Food Stimuli in Overweight Adults.
Effects of Dietary Protein and Fiber at Breakfast on Appetite, ad Libitum Energy Intake at Lunch, and Neural Responses to Visual Food Stimuli in Overweight Adults.
复制标题
DOI：
10.3390/nu8010021
复制
发表时间：
2016-01-05
期刊：
影响因子：
5.9
通讯作者：
Campbell WW
中科院分区：
文献类型：
--
作者：
Sayer RD;Amankwaah AF;Tamer GG Jr;Chen N;Wright AJ;Tregellas JR;Cornier MA;Kareken DA;Talavage TM;McCrory MA;Campbell WW
在用餐时增加蛋白质或纤维对摄入行为的影响相对较小。蛋白质和纤维对摄食行为是否有相加或相互作用尚不清楚。15名超重成人（5名女性，10名男性，BMI: 27.1±0.2 kg/m2，年龄26±1岁）以随机交叉方式（正常蛋白质（12克）+正常纤维（2克），正常蛋白质（12克）+高纤维（8克），高蛋白（25克）+正常纤维（2克），高蛋白（25克）+高纤维（8克））食用4顿早餐。早餐时摄入的蛋白质和纤维量不会影响餐后食欲或午餐时随意摄入的能量。在空腹状态下，视觉食物刺激在双侧脑岛、杏仁核和左眼窝额叶皮层引起显著的反应。与我们的假设相反，与高蛋白早餐相比，食用正常蛋白质早餐后的餐后右脑岛反应更低。早餐摄入蛋白质或纤维对其他先验脑区的餐后反应没有显著影响。总之，这些数据不支持在早餐时增加膳食蛋白质和纤维作为调节神经奖励处理和超重成人急性摄食行为的有效策略。
Increasing either protein or fiber at mealtimes has relatively modest effects on ingestive behavior. Whether protein and fiber have additive or interactive effects on ingestive behavior is not known. Fifteen overweight adults (5 female, 10 male; BMI: 27.1 ± 0.2 kg/m2; aged 26 ± 1 year) consumed four breakfast meals in a randomized crossover manner (normal protein (12 g) + normal fiber (2 g), normal protein (12 g) + high fiber (8 g), high protein (25 g) + normal fiber (2 g), high protein (25 g) + high fiber (8 g)). The amount of protein and fiber consumed at breakfast did not influence postprandial appetite or ad libitum energy intake at lunch. In the fasting-state, visual food stimuli elicited significant responses in the bilateral insula and amygdala and left orbitofrontal cortex. Contrary to our hypotheses, postprandial right insula responses were lower after consuming normal protein vs. high protein breakfasts. Postprandial responses in other a priori brain regions were not significantly influenced by protein or fiber intake at breakfast. In conclusion, these data do not support increasing dietary protein and fiber at breakfast as effective strategies for modulating neural reward processing and acute ingestive behavior in overweight adults.