glypy: An Open Source Glycoinformatics Library
glypy: An Open Source Glycoinformatics Library
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DOI：
10.1021/acs.jproteome.9b00367
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发表时间：
2019-09-01
影响因子：
4.4
通讯作者：
Zaia, Joseph
中科院分区：
文献类型：
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作者：
Klein, Joshua;Zaia, Joseph
糖信息学是糖生物学研究的重要资源，糖生物学是理解细胞内和细胞外空间之间复杂界面的必要组成部分。尽管如此，研究这些主题的科学家可用的软件有限，需要每个人为每个应用程序重新创建基本的数据结构和表示。这导致对标准化的理解不佳，并失去了对真实的问题的关注。我们介绍glypy，一个用Python编写的库，用于阅读、写入、操作和转换多个精度级别的聚糖。除了理解聚糖文本表示的几种常见格式外，该库还为主要的社区数据库提供应用程序编程接口（API），包括GlyTouCan和UnicarbKB。该库在Apache 2通用许可证下免费提供，源代码可在https://github.com/mobiusklein/获得，文档可在https：//www.example.com获得。glypy.readthedocs.io/
Glycoinformatics is a critical resource for the study of glycobiology, and glycobiology is a necessary component for understanding the complex interface between intra- and extracellular spaces. Despite this, there is limited software available to scientists studying these topics, requiring each to create fundamental data structures and representations anew for each of their applications. This leads to poor uptake of standardization and loss of focus on the real problems. We present glypy, a library written in Python for reading, writing, manipulating, and transforming glycans at several levels of precision. In addition to understanding several common formats for textual representation of glycans, the library also provides application programming interfaces (APIs) for major community databases, including GlyTouCan and UnicarbKB. The library is freely available under the Apache 2 common license with source code available at https://github.com/mobiusklein/ and documentation at https:// glypy.readthedocs.io/.