VERRUCOUS CARCINOMA OF THE CERVIX - A REPORT OF 2 CASES AND LITERATURE-REVIEW
VERRUCOUS CARCINOMA OF THE CERVIX - A REPORT OF 2 CASES AND LITERATURE-REVIEW
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DOI：
10.1016/0090-8258(86)90062-4
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发表时间：
1986-09-01
影响因子：
4.7
通讯作者：
BARNARD, DE
中科院分区：
文献类型：
--
作者：
DEGEFU, S;OQUINN, AG;BARNARD, DE
宫颈疣状癌与外阴疣状癌一样，常被误解为外阴湿疣，导致长期延误适当的治疗。由于正确的诊断取决于组织学标准，而组织学标准往往掩盖了这种病变的恶性性质，因此向病理学家传达病变的病史、体格检查结果和临床表现可能有助于早期识别。当局部切除失败时，应考虑将包括内脏切除在内的积极手术作为大病变和复发性病变的主要治疗方法。放射治疗通常不是疣状癌的有效治疗方法，并可能诱发恶变。迄今为止，已报告27例宫颈疣状癌。作者近年来处理的另外两例病例以及对世界上关于这种罕见病变的文献的回顾构成了本报告的基础。
Verrucous carcinoma of the cervix, like verrucous carcinoma of the vulva, is commonly misinterpreted as condyloma accuminata, resulting in a protracted delay of appropriate treatment. Since the correct diagnosis depends upon histological criterion which frequently belies the malignant nature of this lesion, conveyance to the pathologist of the history, physical findings, and clinical behavior of the lesion may facilitate early recognition. Aggressive surgical procedures including exenteration should be considered as primary treatment for large lesions and recurrent lesions when local excision fails. Radiotherapy is not usually an effective treatment for verrucous carcinoma and may induce malignant transformation. To date, 27 cases of verrucous carcinoma of the cervix have been reported. Two additional cases managed in recent years by the authors and a review of the world''s literature about this uncommon lesion form the basis of this report.