Complete genome sequence of Streptomyces vietnamensis GIMV4.0001T, a genetically manipulable producer of the benzoisochromanequinone antibiotic granaticin
Complete genome sequence of Streptomyces vietnamensis GIMV4.0001T, a genetically manipulable producer of the benzoisochromanequinone antibiotic granaticin
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越南链霉菌 GIMV4.0001T 的完整基因组序列，它是苯并异色满醌抗生素granaticin的可基因操作生产者
DOI：
10.1016/j.jbiotec.2015.02.009
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发表时间：
2015
影响因子：
4.1
通讯作者：
Hong-Hui Zhu
中科院分区：
文献类型：
--
作者：
Ming-Rong Deng;Jun Guo;Lian-Ying Ma;Yan-Xuan Li;Guang-Da Feng;Cui-Yun Mo;Hong-Hui Zhu
我们报道了越南链霉菌GIMV4.0001T的完整基因组序列，它是一种新型的、可基因操作的苯并异色满醌抗生素格拉提辛生产者，其独特的糖附着结构模式引起了化学和生化研究人员的广泛关注。越南S.vietnamensisGIMV4.0001T基因组由一条线性染色体（8,867,142 bp，72.09% G + C含量）和一个名为pSVL1的线性大质粒（286,635 bp，69.04% G + C含量）组成，共编码7356个蛋白质编码基因。在染色体上预测了 29 个次生代谢物的基因簇。
We report the complete genome sequence ofStreptomyces vietnamensisGIMV4.0001T, a new and genetically manipulable producer of the benzoisochromanequinone antibiotic granaticin, whose unique sugar attachment pattern in structure has drawn much attention among chemical and biochemical researchers. The genome ofS.vietnamensisGIMV4.0001Tconsists of one linear chromosome (8,867,142 bp, 72.09% G + C content) and one linear megaplasmid named pSVL1 (286,635 bp, 69.04% G + C content), encoding a total of 7356 protein coding genes. Twenty-nine gene clusters for secondary metabolites were predicted on the chromosome.