An association between smoking habits and blood pressure in normotensive Japanese men
An association between smoking habits and blood pressure in normotensive Japanese men
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DOI：
10.1038/sj.jhh.1001303
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发表时间：
2002-02-01
影响因子：
2.7
通讯作者：
Nogawa, K
中科院分区：
文献类型：
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作者：
Okubo, Y;Miyamoto, T;Nogawa, K
我们进行了一项横断面研究，以澄清日本男性吸烟习惯与血压之间的剂量-效应关系。研究对象为2781名血压正常的男性钢铁工人，年龄40~54岁。根据他们的吸烟习惯，他们被分为五类：不吸烟者、前吸烟者、轻度吸烟者、中度吸烟者和重度吸烟者。协变量包括年龄、体重指数、食盐摄入量、体力活动、饮酒习惯、γ-谷氨酰转肽酶、血清总胆固醇、尿酸、肌酐和血糖。通过协方差分析评估吸烟习惯与血压之间的关系。我们的结果显示，调整后的收缩压和舒张压在非吸烟者和戒烟者之间没有显著差异。轻度吸烟者、中度吸烟者和重度吸烟者的调整后收缩压和舒张压显著低于不吸烟者和戒烟者。但在吸烟者中，与吸烟量的相关性无显著差异。综上所述，吸烟者的血压低于不吸烟者和戒烟者。然而，当考虑生活方式和其他混杂因素时，吸烟量与血压之间没有显著的剂量-效应关系。
We conducted a cross-sectional study to clarify the dose-effect relationship of smoking habits with blood pressure In Japanese men. The subjects were 2781 normotensive male steelworkers ranging in age from 40 to 54 years. They were classified into five categories according to their smoking habits: non-smokers, ex-smokers, light smokers, moderate smokers and heavy smokers. Age, body mass Index, salt intake, physical activity, drinking habits, and levels of gamma-glutamyl transpeptidase, total serum cholesterol, uric acid, creatinine and plasma glucose were analysed as covariates. The association between smoking habits and blood pressure was evaluated using analysis of covariance. Our results showed that there was no significant difference in the adjusted systolic and diastolic blood pressure between non-smokers and ex-smokers. The adjusted systolic and diastolic blood pressures in light, moderate and heavy smokers were significantly lower than in non- and ex-smokers. However, among smokers, no significant difference was observed in correlation with smoking amount. In conclusion, blood pressure of smokers was lower than that of non- and ex-smokers. However, there were no significant dose-effect relationships between smoking amount and blood pressure when lifestyle and other confounding factors were considered.