Radiation-Induced Cholecystitis after Hepatic Radioembolization: Do We Need to Take Precautionary Measures?
Radiation-Induced Cholecystitis after Hepatic Radioembolization: Do We Need to Take Precautionary Measures?
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DOI：
10.1016/j.jvir.2014.06.024
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发表时间：
2014-11-01
影响因子：
2.9
通讯作者：
Lam, Marnix G. E. H.
中科院分区：
文献类型：
--
作者：
Prince, Jip F.;van den Hoven, Andor F.;Lam, Marnix G. E. H.
在肝放射性栓塞术期间是否需要采取预防措施以最大限度地降低放射性胆囊炎的风险存在争议。各种临床方案的战略进行了讨论的基础上，文献综述。大多数患者不需要采取预防措施，只有当单光子发射计算机断层扫描（CT; SPECT）/CT显示胆囊壁中存在显著浓度的锝-99 m大颗粒聚集白蛋白时，才应采取预防措施。在本病例报告中，定量SPECT分析，它说明了如何调整导管位置可以有效地减少超过90%的辐射输送到胆囊壁的吸收剂量。
Controversy exists over the need to take precautionary measures during hepatic radioembolization to minimize the risk of radiation-incluced cholecystitis. Strategies for a variety of clinical scenarios are discussed on the basis of a literature review. Precautionary measures are unnecessary in the majority of patients and should be taken only when single photon-emission computed tomography (CT; SPECT)/CT shows a significant concentration of technetium-99m macroaggregated albumin in the gallbladder Wall. In this case report with quantitative SPECT analysis, it is illustrated how an adjustment of the catheter position can effectively reduce the absorbed dose of radiation delivered to the gallbladder wall by more than 90%.