Arthritis after infection with Chikungunya virus

Arthritis after infection with Chikungunya virus
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DOI:
10.1016/j.berh.2011.03.005
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发表时间:
2011-06-01
影响因子:
5.2
通讯作者:
Combe, Bernard
Combe, Bernard
中科院分区:
医学2区
文献类型:
--
作者:
Alla, Sanae Ali Ou;Combe, Bernard

文献摘要

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基孔肯雅病毒(CHIKV)是一种新出现的甲病毒,在世界范围内引起了几次传染病暴发。在以发热-关节痛综合征和皮疹为特征的疾病急性期之后,由于CHIKV感染引起的关节疾病有时会持续数月或数年。慢性关节炎后,这种新兴的疾病是有据可查的,和相似之处,类风湿性关节炎已被描述。了解CHIKV感染的地理流行病学对于更好地控制该疾病至关重要。因此,最近的爆发导致了几项研究,这些研究强调了需要更好地了解基孔肯雅热(CHIK)的临床特征,并开始了解病理生理发生,这可能会导致进一步的研究。(C)2011爱思唯尔有限公司保留所有权利。
Chikungunya virus (CHIKV) is an emerging alphavirus responsible for several infectious outbreaks in the world. After an acute stage of illness characterised by a fever-arthralgia syndrome and rash, joint disorders due to CHIKV infection can sometimes persist for several months or years. Chronic arthritis after this emerging disease is well documented, and similarities to rheumatoid arthritis have been described. Knowledge of the geographical epidemiology of CHIKV infection is crucial for better control of the disease. Thus, recent outbreaks have led to several studies, which have highlighted the need for a better understanding of the clinical features of Chikungunya (CHIK) and beginning knowledge of the pathophysiogenesis, which can lead to further research. (C) 2011 Elsevier Ltd. All rights reserved.