Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya
Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya
复制标题
DOI：
10.1086/430006
复制
发表时间：
2005-06-01
影响因子：
6.4
通讯作者：
Marsh, K
中科院分区：
文献类型：
--
作者：
Mwangi, TW;Ross, A;Marsh, K
背景明确的疟疾病例定义是评价目前和拟议的疟疾干预措施有效性的一个重要手段。疟疾的临床症状是非特异性的，寄生虫血症伴发发热可能不足以确定流行地区的临床疟疾发作。我们定义并量化了来自两个疟疾传播率不同地区的不同年龄组人群的疟疾病例。共随访1602人，每周一次，为期2年，并确定了所有发热伴寄生虫血症的病例。采用Logistic回归方法得出疟疾的病例定义。疟疾的两个病例定义：1为1-14岁的儿童，1为婴儿（
Background. Clear case definitions of malaria are an essential means of evaluating the effectiveness of present and proposed interventions in malaria. The clinical signs of malaria are nonspecific, and parasitemia accompanied by a fever may not be sufficient to define an episode of clinical malaria in endemic areas. We defined and quantified cases of malaria in people of different age groups from 2 areas with different rates of transmission of malaria.Methods. A total of 1602 people were followed up weekly for 2 years, and all the cases of fever accompanied by parasitemia were identified. Logistic regression methods were used to derive case definitions of malaria.Results. Two case definitions of malaria were derived: 1 for children 1-14 years old and 1 for infants (