USE OF THE PERCEPTRON ALGORITHM TO DISTINGUISH TRANSLATIONAL INITIATION SITES IN ESCHERICHIA-COLI
USE OF THE PERCEPTRON ALGORITHM TO DISTINGUISH TRANSLATIONAL INITIATION SITES IN ESCHERICHIA-COLI
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DOI：
10.1093/nar/10.9.2997
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发表时间：
1982-01-01
影响因子：
14.9
通讯作者：
EHRENFEUCHT, A
中科院分区：
文献类型：
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作者：
STORMO, GD;SCHNEIDER, TD;EHRENFEUCHT, A
我们使用“Perceptron”算法找到一个加权函数，该函数在超过78，000个核苷酸的mRNA序列的文库中从所有其他位点中排除大肠杆菌的翻译起始位点。“感知器”将序列作为线性表示进行检查。“感知器”在寻找基因起点方面比我们以前使用“规则”的搜索更成功（见以前的论文）。我们注意到，加权函数可以找到未包括在训练集中的序列内的翻译起始位点。
We have used a “Perceptron” algorithm to find a weighting function which distinguishesE.colitranslational initiation sites from all other sites in a library of over 78,000 nucleotides of mRNA sequence. The “Perceptron” examined sequences as linear representations. The “Perceptron” is more successful at finding gene beginnings than our previous searches using “rules” (see previous paper). We note that the weighting function can find translational initiation sites within sequences that were not included in the training set.