Microwave assisted selective oxidation of lignin model phenolic monomer over SBA-15
Microwave assisted selective oxidation of lignin model phenolic monomer over SBA-15
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DOI：
10.1016/j.catcom.2008.04.012
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发表时间：
2008-07-20
影响因子：
3.7
通讯作者：
Breeden, Simon W.
中科院分区：
文献类型：
--
作者：
Badamali, Sushanta K.;Clark, James H.;Breeden, Simon W.
以介孔分子筛SBA-15为催化剂，H2O2为氧化剂，微波辅助氧化木质素模型单体1-（4-羟基-3-甲氧基苯氧基）-乙醇，合成了乙酰香草酮、香草醛和2-甲氧基苯醌。优化了反应条件，以选择性地获得乙酰香草酮，其用作3，4-二甲氧基苯甲酸的原料，3，4-二甲氧基苯甲酸是合成平滑肌松弛剂美贝维林的结构单元。在常规加热条件下，反应缓慢，产物混合物的产率低。催化剂用量的增加导致乙酰香草酮选择性的降低。并对催化剂循环使用的可能性进行了研究。(C)2008年由Elsevier B.V.出版。
Microwave assisted oxidation of the lignin model monomer apocynol, 1-(4-hydroxy-3-methoxyphenoxy)-ethanol was carried out over mesoporous SBA-15 catalyst using H2O2 as oxidant to produce acetovanillone, vanillin and 2-methoxybenzoquinone. Reaction conditions were optimised in order to obtain acetovanillone selectively, which serves as a raw material for 3,4-dimethoxybenzoic acid, a building block for synthesis of the smooth muscle relaxant mebeverin. Under conventional heating reactions were sluggish and gave poor yields of a mixture of products. The use of increased amount of catalyst resulted in lowering of acetovanillone selectivity. The possibility of recycling the catalyst was also studied. (C) 2008 Published by Elsevier B.V.