THE 2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL GROUP (PBF) AS ARGININE SIDE-CHAIN PROTECTANT
THE 2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL GROUP (PBF) AS ARGININE SIDE-CHAIN PROTECTANT
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DOI：
10.1016/s0040-4039(00)61487-9
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发表时间：
1993-12-03
影响因子：
1.8
通讯作者：
ALBERICIO, F
中科院分区：
文献类型：
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作者：
CARPINO, LA;SHROFF, H;ALBERICIO, F
2，2，4，6，7-五甲基二氢苯并呋喃-5-磺酰基残基（Pbf）比相应的Pmc类似物更容易被三氟乙酸（TFA）去封闭，并且可以有效地用于合成含精氨酸的肽。
The 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl residue (Pbf) is more easily deblocked by trifluoroacetic acid (TFA) than the corresponding Pmc analog and can be used efficiently in the synthesis of arginine-containing peptides.