P2Y12 inhibition in patients with NSTEMI--can later be better?
P2Y12 inhibition in patients with NSTEMI--can later be better?
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NSTEMI 患者的 P2Y12 抑制——以后会更好吗？
DOI：
10.1056/nejme1308820
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
KeaneyJr,JohnF
中科院分区：
文献类型：
--
作者：
KeaneyJr,JohnF
急性冠状动脉综合征是一个总括性术语，用于描述流向心肌组织的血流突然减少，通常与冠状动脉粥样硬化斑块破裂有关。破裂使血液暴露于斑块内容物，导致血小板沉积和活化以及血栓形成。完全血栓性闭塞导致ST段抬高型心肌梗死，而冠状动脉血流不完全受损导致不稳定型心绞痛，或者当存在心肌损伤的生物标志物时，导致非ST段抬高型心肌梗死（NSTEMI）。由于斑块破裂会刺激血小板活化和血栓形成，不稳定型心绞痛和非ST段抬高型心肌梗死的治疗…
Acute coronary syndrome is an umbrella term that is used to describe the abrupt reduction of blood flow to myocardial tissue, typically associated with the rupture of a coronary atherosclerotic plaque. Rupture exposes the blood to plaque contents, resulting in the deposition and activation of platelets and the formation of thrombi. Complete thrombotic occlusion produces ST-segment elevation myocardial infarction, whereas incomplete impairment of coronary blood flow results in unstable angina or, when biomarkers for myocardial injury are present, non–ST-segment elevation myocardial infarction (NSTEMI). Because the rupture of a plaque incites platelet activation and thrombosis, treatments for unstable angina and NSTEMI . . .