Living Donor Liver Transplantation: The Asian Perspective
Living Donor Liver Transplantation: The Asian Perspective
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DOI：
10.1097/tp.0000000000000060
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发表时间：
2014-04-27
期刊：
影响因子：
6.2
通讯作者：
Chen, Chao-Long
中科院分区：
文献类型：
--
作者：
Cheng, Yu-Fan;Yu, Chun-Yen;Chen, Chao-Long
活体肝移植供体的术前评估旨在选择具有最佳移植质量的合适供体，确保供体安全。肝脏脂肪变性是活体供肝的常见表现，不仅影响受者肝移植的效果，而且影响活体供肝部分切除后的恢复。组织病理学分析是检测和量化肝脏脂肪的参考标准，但它具有侵入性，结果容易受到抽样误差的影响。成像可以定期重复，并允许对整个肝脏进行评估，从而避免抽样误差。选择合适的成像方法需要了解它们的优点和局限性以及合适的临床环境。本文介绍了肝脏脂肪定量的成像方法在临床上的潜在应用，重点介绍了超声、计算机断层扫描和磁共振成像在肝脏脂肪定量方面的优势和局限性。
Preoperative evaluation of donors for living-donor liver transplantation aims to select a suitable donor with optimal graft quality and to ensure donor safety. Hepatic steatosis, a common finding in living liver donors, not only influences the outcome of liver transplantation for the recipient but also affects the recovery of the living donor after partial hepatectomy. Histopathologic analysis is the reference standard to detect and quantify fat in the liver, but it is invasive, and results are vulnerable to sampling error. Imaging can be repeated regularly and allows assessment of the entire liver, thus avoiding sampling error. Selection of appropriate imaging methods demands understanding of their advantages and limitations and the suitable clinical setting. This article describes potential clinical applications for liver fat quantification of imaging methods for fat detection and quantification, with an emphasis on the advantages and limitations of ultrasonography, computed tomography, and magnetic resonance imaging for quantifying liver fat.