Activity of the motor cortex during scratching.
Activity of the motor cortex during scratching.
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抓挠期间运动皮层的活动。
DOI：
10.1152/jn.00050.2005
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Beloozerova,IrinaN
中科院分区：
文献类型：
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作者：
Sirota,MikhailG;Pavlova,GalinaA;Beloozerova,IrinaN
在清醒的猫坐在与头部约束，抓挠诱发使用耳朵的刺激。猫抓挠肩膀区域，总是抓不到耳朵。然而，后肢运动和踝关节肌肉的活动的kinetics，是类似于先前报道的不受约束的猫。单个神经元的活动在后肢代表的运动皮层，包括锥体束神经元（PTNs），进行了检查。在抓挠反应的延长阶段，35%的神经元的活性增加，50%的神经元的活性降低。在节律阶段，运动皮层群体活动比休息时高约两倍，因为在这个阶段，53%的神经元的活动增加，33%的神经元的活动减少。61%的神经元的活动在抓挠节律中受到调制。频率调制的平均深度为12.1 ± 5.3%，与早期报道的运动相似。不同神经元的活动阶段大致均匀分布在划痕周期。静息感受野特性与抓挠反应期间神经元的活动之间没有简单的相关性。我们的结论是，运动皮层参与了延长和节奏阶段的划痕反应。
In awake cats sitting with the head restrained, scratching was evoked using stimulation of the ear. Cats scratched the shoulder area, consistently failing to reach the ear. Kinematics of the hind limb movements and the activity of ankle muscles, however, were similar to those reported earlier in unrestrained cats. The activity of single neurons in the hind limb representation of the motor cortex, including pyramidal tract neurons (PTNs), was examined. During the protraction stage of the scratch response, the activity in 35% of the neurons increased and in 50% decreased compared with rest. During the rhythmic stage, the motor cortex population activity was approximately two times higher compared with rest, because the activity of 53% of neurons increased and that of 33% decreased in this stage. The activity of 61% of neurons was modulated in the scratching rhythm. The average depth of frequency modulation was 12.1 ± 5.3%, similar to that reported earlier for locomotion. The phases of activity of different neurons were approximately evenly distributed over the scratch cycle. There was no simple correlation between resting receptive field properties and the activity of neurons during the scratch response. We conclude that the motor cortex participates in both the protraction and the rhythmic stages of the scratch response.