The velocity distribution in the aortic annulus at different times during systole is mainly determined by the pattern of flow convergence in the left ventricular outflow tract--an experimental study using Doppler colour flow mapping.
The velocity distribution in the aortic annulus at different times during systole is mainly determined by the pattern of flow convergence in the left ventricular outflow tract--an experimental study using Doppler colour flow mapping.
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收缩期不同时间主动脉环的速度分布主要由左心室流出道的血流汇聚模式决定——这是一项使用多普勒彩色血流图的实验研究。
DOI：
10.1111/j.1475-097x.1995.tb00547.x
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
P. Husby
中科院分区：
文献类型：
--
作者：
Y. Q. Zhou;S. Faerestrand;S. Birkeland;K. Matre;M. Koller;P. Husby
对10只开胸正常猪（体重：24±1kg）进行实验研究，探讨主动脉环内速度分布与左心室流出道血流汇聚模式之间的关系。主动脉环的横截面速度分布是通过使用多普勒彩色血流映射和先前验证的时间插值方法构建的。通过测量主动脉环中心轴前后两侧的彩色血流面积并计算它们的差异来量化左心室流出道中的血流汇聚模式。观察整个收缩期速度分布、血流汇聚模式和间隔角度的动态变化。主动脉环中的速度分布根据左心室流出道中的血流汇聚模式而变化。在收缩早期，血流汇聚模式最不对称。以主动脉环中心纵轴为参考，汇聚血流的主要部分是沿着左心室流出道的前壁。因此，主动脉环内的速度分布在收缩早期最为倾斜，沿前壁的速度最高。到收缩后期，血流汇聚模式变得越来越对称，主动脉环内的速度分布逐渐变得平坦。左心室流出道血流汇聚模式的不对称程度与主动脉环内速度分布的偏度程度之间存在显着相关性（r = 0.69，P < 0.001）。在整个收缩期，间隔角度略有增加（从 35 +/- 3 度到 38 +/- 3 度，P < 0.01）。左心室流出道中的血流汇聚模式是猪主动脉环中速度分布的主要决定因素。
An experimental study in 10 open chest normal pigs (body weight: 24 +/- 1 kg) was carried out to explore the relationship between the velocity distribution in the aortic annulus and the pattern of flow convergence in the left ventricular outflow tract. The cross-sectional velocity profiles in the aortic annulus were constructed by using Doppler colour flow mapping with a previously validated time-interpolation method. The pattern of flow convergence in the left ventricular outflow tract was quantified by measuring the colour flow areas on the anterior and posterior sides of the central axis of the aortic annulus, and calculating their difference. The dynamic changes of the velocity distribution, the pattern of flow convergence and the septal angle throughout systole were observed. The velocity distribution in the aortic annulus changed according to the pattern of flow convergence in the left ventricular outflow tract. During early systole, the pattern of flow convergence was most asymmetrical. With the central longitudinal axis of the aortic annulus as a reference, the main part of the converging flow was along the anterior wall of the left ventricular outflow tract. Consequently, the velocity profile in the aortic annulus was most skewed during the early systole, with the highest velocity along the anterior wall. Towards late systole, the pattern of flow convergence became more and more symmetrical, and the velocity distribution in the aortic annulus gradually became flat. A significant correlation was found between the extent of asymmetry of the pattern of flow convergence in the left ventricular outflow tract and the extent of skewness of the velocity distribution in the aortic annulus (r = 0.69, P < 0.001). Throughout systole, septal angle increased very slightly (from 35 +/- 3 to 38 +/- 3 degrees, P < 0.01). The pattern of flow convergence in the left ventricular outflow tract is a major determinant of the velocity distribution in the aortic annulus in pigs.