Characterization of Balance Control and Postural Stability in Patients With Alzheimer Disease.
Characterization of Balance Control and Postural Stability in Patients With Alzheimer Disease.
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阿尔茨海默病患者平衡控制和姿势稳定性的特征。
DOI：
10.1097/wad.0000000000000548
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发表时间：
2023
影响因子：
2.1
通讯作者：
Agrawal,Yuri
中科院分区：
文献类型：
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作者：
So,RaymondJ;Biju,Kevin;Oh,Esther;Rosenberg,Paul;Xue,Qian-Li;Dash,Paul;Burhanullah,MuhammadH;Agrawal,Yuri
阿尔茨海默病（AD）患者的平衡尚未得到严格理解。在这项研究中，我们使用定性[贝格平衡量表（BBS）]和定量措施（姿势描记法）的特点，并评估定性和定量的平衡措施之间的关系在AD。招募了轻中度AD患者（n= 48）。在睁眼和闭眼条件下评估BBS评分和姿势图指标，包括内外侧摇摆范围、前后摇摆范围、摇摆面积和摇摆速度。校正线性回归用于评估姿势图和BBS评分之间的关系。平均BBS评分为50.4±5.3。在睁眼条件下，姿势图和BBS评分无显著相关性。在闭眼条件下，更好的BBS评分与更低的摇摆面积显著相关（β=-0.91; P= 0.006）。更好的分数BBS项目涉及转向和减少基地的支持与更大的闭眼摇摆区。在更具挑战性的闭眼条件下的姿势图可以预测AD患者的功能平衡缺陷。
Balance in Alzheimer disease (AD) patients is not rigorously understood. In this study, we characterize balance using qualitative [Berg Balance Scale (BBS)] and quantitative measures (posturography) and assess relationships between qualitative and quantitative balance measures in AD. Patients with mild-moderate AD (n= 48) were recruited. BBS scores and posturography metrics, including medial-lateral sway range, anterior-posterior sway range, sway area, and sway velocity, were assessed in eyes-open and eyes-closed conditions. Adjusted linear regressions were used to assess relationships between posturography and BBS score. Mean BBS score was 50.4±5.3. In eyes-open conditions, posturography and BBS score were not significantly associated. In eyes-closed conditions, better BBS score was significantly associated with lower sway area (β=− 0.91; P= 0.006). Better scores of BBS items involving turning and reduced base of support were associated with greater eyes-closed sway area. Posturography in the more challenging eyes-closed condition may predict functional balance deficits in AD patients.