High strength graphene oxide/polyvinyl alcohol composite hydrogels
High strength graphene oxide/polyvinyl alcohol composite hydrogels
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DOI：
10.1039/c0jm04043f
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发表时间：
2011-07
影响因子：
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通讯作者：
Lu Zhang;Zhipeng Wang;Chen Xu;Yi Li;Jian-ping Gao;Wen Wang;Yu Liu
中科院分区：
文献类型：
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作者：
Lu Zhang;Zhipeng Wang;Chen Xu;Yi Li;Jian-ping Gao;Wen Wang;Yu Liu
已经提出了聚乙烯醇（PVA）水凝胶作为生物医学和组织工程中有前途的生物材料，但其机械和退水性能较差已阻碍了它们的发展。氧化石墨烯（GO）是一种出色的纳米熔剂，通过冻结/解冻方法添加到PVA中，以制造GO/PVA复合水凝胶。 GO/PVA水凝胶的机械性能得到了显着提高。与纯PVA水凝胶相比，加入0.8 wt％的GO，抗拉力强度提高了132％，抗压强度提高了36％，这表明GO和PVA基质之间具有出色的负载转移。将一定量的GO掺入复合水凝胶不会影响PVA对成骨细胞的毒性。
Polyvinyl alcohol (PVA) hydrogels have been proposed for use as promising biomaterials in biomedical and tissue engineering but their poor mechanical and water-retention properties have hindered their development. Graphene oxide (GO), an excellent nanofiller, was added to PVA to make GO/PVA composite hydrogels by a freeze/thaw method. The mechanical properties of the GO/PVA hydrogels were significantly improved. Compared to pure PVA hydrogels, a 132% increase in tensile strength and a 36% improvement of compressive strength were achieved with the addition of 0.8 wt% of GO, which suggests an excellent load transfer between the GO and the PVA matrix. The incorporation of certain amount of GO into composite hydrogels does not affect the toxicity of PVA to osteoblast cells.