H+-induced tension development in demineralized dentin matrix
H+-induced tension development in demineralized dentin matrix
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DOI：
10.1177/00220345000790080901
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发表时间：
2000-08-01
影响因子：
7.6
通讯作者：
Russell, CM
中科院分区：
文献类型：
--
作者：
Pashley, DH;Zhang, Y;Russell, CM
最近的原子力显微镜研究表明，酸蚀牙本质导致表面退缩。本研究旨在验证酸性溶液可引起脱矿牙本质基质收缩的假设。从人的第三磨牙上切下小束的牙本质。每个样本的中心区域在EDTA中完全脱矿质。将保持在测试仪中的样本浸入酸性溶液中，并记录张力的量。测试变量包括标距长度，横截面积，预应变，和pH值。结果表明，浸泡脱矿牙本质在酸性溶液中引起的张力，这是直接相关的H+浓度在pH值< 2和预应变。收缩应力的发展（CA。0.2- 0.4MPa）足以引起脱矿牙本质基质的塌陷。这种效应的机制可能涉及H+诱导的胶原基质构象变化。
Recent atomic force microscopy studies have shown that acid-etching dentin causes the surface to recede. The purpose of this work was to test the hypothesis that acidic solutions can cause contraction of demineralized dentin matrix. Small beams of dentin were cut from extracted human third molars. The central region of each specimen was completely demineralized in EDTA. Specimens held in a tester were immersed in acidic solutions, and the amount of tension was recorded. Test variables included gauge length, cross-sectional area, pre-strain, and pH. The results showed that immersion of demineralized dentin in acidic solutions caused tension that was directly related both to H+ concentration at pH < 2 and to pre-strain. The contractile stress development (ca. 0.2-0.4 MPa) was sufficient to cause a collapse of demineralized dentin matrix. The mechanism for this effect probably involves H+-induced conformation changes in the collagen matrix.