Ghrelin in birds: Its structure, distribution and function
Ghrelin in birds: Its structure, distribution and function
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DOI：
10.2141/jpsa.44.1
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发表时间：
2007-01-01
影响因子：
1.5
通讯作者：
Kangawa, Kenji
中科院分区：
文献类型：
--
作者：
Kaiya, Hiroyuki;Darras, Veerle M.;Kangawa, Kenji
摄食和躯体生长密切相关，并严格受动物体内多个内分泌和神经内分泌系统的控制。家禽生长的内分泌调控是家禽养殖业的重要课题。Ghrelin是一种新近发现的哺乳动物生长激素释放肽，主要来源于胃。从比较内分泌学的角度来看，Ghrelin被认为存在于鸟类物种中。事实上，在2002年已经从鸡前胃中鉴定出了生长素释放肽肽及其编码生长素释放肽前体的cDNA，并且生长素释放肽分子的存在现在已经在各种鸟类物种中显示。本文综述了ghrelin在鸟类中的结构、分布和功能。
Feeding and somatic growth are closely related to each other, and are strictly governed by several endocrine and neuroendocrine systems in animals. Endocrine control of growth is an important subject in poultry industry. Ghrelin is a recently identified, growth hormone (GH)-releasing and feeding-promoting peptide in mammals, and the major source of its release is the stomach. From the comparative endocrinological aspects, ghrelin was considered to be present in avian species. In fact, ghrelin peptide and its cDNA encoding ghrelin precursor have been identified from the chicken proventriculus in 2002, and the presence of the ghrelin molecule has by now been shown in various avian species. In this review, we summarize the recent knowledge of ghrelin structure, distribution and function in birds.