Clonorchis sinensis infection and increasing risk of cholangiocarcinoma in the Republic of Korea

Clonorchis sinensis infection and increasing risk of cholangiocarcinoma in the Republic of Korea
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DOI:
10.4269/ajtmh.2006.75.93
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发表时间:
2006-07-01
影响因子:
3.3
通讯作者:
Shin, Hai-Rim
Shin, Hai-Rim
中科院分区:
医学4区
文献类型:
--
作者:
Lim, Min Kyung;Ju, Young-Hee;Shin, Hai-Rim

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为了评估华支睾吸虫感染的患病率和危险因素,在胆管癌死亡率不同的三个地区进行了流行病学调查(3,169名居民;年龄范围:30-87岁;平均年龄= 59岁; 1,973名女性)。C.中国人的患病率在春川为2.1%,忠州为7.8%,哈曼为31.3%,胆管癌的发病率分别为每10万人0.3、1.8和5.5。在C.中国人(男性、饮酒量、生食淡水鱼摄入量、居住地)、居住地最强。努力阻止生淡水鱼的摄入,治疗卵携带者,保护水源免受C。应加强韩国的中华民国污染。
To evaluate the prevalence and risk factors of Clonorchis sinensis infection, an epidemiologic survey was performed (3,169 residents; age range: 30-87 years; mean age = 59; 1,973 women) in three areas with different mortality rates of cholangiocarcinoma. C. sinensis prevalence was 2.1% in Chuncheon, 7.8% in Chungju, and 31.3% in Haman, where cholangiocarcinoma incidence rate was 0.3, 1.8, and 5.5 per 100,000 persons, respectively. Of the four major risk factors for C. sinensis (male sex, alcohol consumption, raw freshwater fish intake, and area of residence), area was the strongest. Efforts to discourage raw freshwater fish intake, treat egg carriers, and protect water sources from C. sinensis contamination should be strengthened in the Republic of Korea.