Visuomotor strategies for object approach and aversion in Drosophila melanogaster
Visuomotor strategies for object approach and aversion in Drosophila melanogaster
复制标题
DOI：
10.1242/jeb.193730
复制
发表时间：
2019-02-01
影响因子：
2.8
通讯作者：
Frye, Mark A.
中科院分区：
文献类型：
--
作者：
Mongeau, Jean-Michel;Cheng, Karen Y.;Frye, Mark A.
动物对刺激进行分类，以产生适当的运动动作。在飞行中，黑腹果蝇将等距离的大物体和小物体分类为具有绝对不同行为的物体：高的物体引起接近，而小的物体引起回避。我们研究了硬系和磁系的黑腹龙的视觉运动行为，以揭示对小物体产生厌恶的策略。我们发现系绳飞行中的小物体厌恶是由厌恶扫视和平滑运动引起的，它们随刺激类型而变化。短杆下的厌恶性扫视与高杆下的趋近性扫视具有不同的动态特性，短杆下的扫视前误差角分布更具随机性。综上所述，我们发现黑腹龙的厌恶反应在一定程度上是由诱发具有不同动力学和触发机制的手语扫视的过程驱动的。我们的工作产生了新的假设来研究黑腹龙对物体分类的大脑回路。
Animals classify stimuli to generate appropriate motor actions. In flight, Drosophila melanogaster classify equidistant large and small objects with categorically different behaviors: a tall object evokes approach whereas a small object elicits avoidance. We studied visuomotor behavior in rigidly and magnetically tethered D. melanogaster to reveal strategies that generate aversion to a small object. We discovered that small-object aversion in tethered flight is enabled by aversive saccades and smooth movement, which vary with the stimulus type. Aversive saccades in response to a short bar had different dynamics from approach saccades in response to a tall bar and the distribution of pre-saccade error angles was more stochastic for a short bar. Taken together, we show that aversive responses in D. melanogaster are driven in part by processes that elicit signed saccades with distinct dynamics and trigger mechanisms. Our work generates new hypotheses to study brain circuits that underlie classification of objects in D. melanogaster.