Autoimmune-like pancreatitis in thymoma with myasthenia gravis.
Autoimmune-like pancreatitis in thymoma with myasthenia gravis.
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胸腺瘤伴重症肌无力的自身免疫样胰腺炎。
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
C. Sartori
中科院分区：
文献类型：
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作者：
F. Colaut;L. Toniolo;C. Sperti;M. Pozzobon;Antonio Scapinello;C. Sartori
一位胸腺瘤合并重症肌无力的病人因手术而入院，表现为血清胰淀粉酶和脂肪酶水平升高。怀疑胸腺瘤相关的自身免疫性疾病，测定自身抗体血清滴度：检测到乙酰胆碱受体、甲状腺球蛋白、甲状腺过氧化物酶和胰腺胰岛素的自身抗体滴度增加。胸腺切除后血清胰酶水平迅速下降。重症肌无力症状也得到改善。据我们所知，文献中没有类似的病例报告。
A patient with thymoma and myasthenia gravis admitted for surgery presented increased serum levels of pancreatic amylase and lipase. Suspecting a thymoma-related autoimmune disorder, autoantibody serum titers were determined: increased autoantibody titers to acetylcholine receptors, thyroglobulin, thyroperoxidase and pancreatic insulin were detected. After thymectomy the serum levels of pancreatic enzymes decreased rapidly. Myasthenia gravis symptoms also improved. To the best of our knowledge no similar cases have been reported in the literature.