Systematic review of reversible cerebral vasoconstriction syndrome.
Systematic review of reversible cerebral vasoconstriction syndrome.
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DOI：
10.1586/erc.10.124
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发表时间：
2010-10
影响因子：
2
通讯作者：
Jensen MB
中科院分区：
文献类型：
--
作者：
Sattar A;Manousakis G;Jensen MB
可逆性脑血管收缩综合征（RCVS）是一种与多灶性动脉收缩和扩张相关的脑血管疾病。RCVS与非蛛网膜下腔出血、妊娠和某些药物暴露有关。主要临床表现为1-3周内反复发作的突发性和严重（“霹雳”）头痛，通常伴有恶心、呕吐、恐惧症、意识模糊和视力模糊。主要的诊断难题是区分RCVS和原发性CNS动脉炎。诊断需要在1-3个月内在脑血管造影上显示特征性的“串珠状”，尽管许多患者最初的血管成像正常。据报道，许多治疗方法可以改善RCVS的头痛，但尚不清楚它们是否可以预防出血或缺血性并发症。
Reversible cerebral vasoconstriction syndrome (RCVS) is a cerebrovascular disorder associated with multifocal arterial constriction and dilation. RCVS is associated with nonaneurysmal subarachnoid hemorrhage, pregnancy and exposure to certain drugs. The primary clinical manifestation is recurrent sudden-onset and severe (‘thunderclap’) headaches over 1–3 weeks, often accompanied by nausea, vomiting, photophobia, confusion and blurred vision. The primary diagnostic dilemma is distinguishing RCVS from primary CNS arteritis. Diagnosis requires demonstration of the characteristic ‘string of beads’ on cerebral angiography with resolution within 1–3 months, although many patients will initially have normal vascular imaging. Many treatments have been reported to ameliorate the headaches of RCVS, but it is unclear whether they prevent hemorrhagic or ischemic complications.