Response to Comment on Hinnouho et al. Metabolically Healthy Obesity and Risk of Mortality: Does the Definition of Metabolic Health Matter? Diabetes Care 2013;36:2294–2300
Response to Comment on Hinnouho et al. Metabolically Healthy Obesity and Risk of Mortality: Does the Definition of Metabolic Health Matter? Diabetes Care 2013;36:2294–2300
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DOI：
10.2337/dc14-0101
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发表时间：
2014-04
期刊：
影响因子：
16.2
通讯作者：
Guy-Marino Hinnouho;S. Czernichow;A. Singh‐Manoux
中科院分区：
文献类型：
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作者：
Guy-Marino Hinnouho;S. Czernichow;A. Singh‐Manoux
我们感谢dr。Doehner和Pfeiffer(1)对我们关于代谢健康型肥胖（MHO）表型与死亡率之间关系的文章(2)的回复。我们使用了代谢健康的五种定义来表明，对于大多数代谢健康的定义，代谢健康和不健康的肥胖患者都具有相似的死亡率升高的风险。Doehner和Pfeiffer并没有质疑我们的研究结果与MHO表型相关的有效性，但他们认为超重和肥胖可能对老年人和慢性病患者无害。他们建议“体重管理应该……
We thank Drs. Doehner and Pfeiffer (1) for their letter in response to our article (2) on the association of metabolically healthy obese (MHO) phenotype with mortality. We used five definitions of metabolic health to show that for most definitions of metabolic health both metabolically healthy and unhealthy obese patients carry a similar, elevated risk of mortality. Doehner and Pfeiffer do not question the validity of our findings in relation to the MHO phenotype, but suggest that overweight and obesity may not be harmful at older ages and in those with a chronic disease. They suggest that “weight management should be …