Children prenatally exposed to cocaine: Developmental outcomes and environmental risks at seven years of age

Children prenatally exposed to cocaine: Developmental outcomes and environmental risks at seven years of age
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DOI:
10.1097/00004703-200404000-00002
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发表时间:
2004-04-01
影响因子:
2.4
通讯作者:
Flannery, D
Flannery, D
中科院分区:
医学4区
文献类型:
--
作者:
Arendt, RE;Short, EJ;Flannery, D

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关于学龄儿童产前接触可卡因的长期后果,数据不明确。我们比较了101名产前接触可卡因的儿童和130名未接触可卡因的儿童在7岁时的智力、视觉运动和运动能力。双变量分析显示,可卡因暴露的儿童得分显着低于对照组儿童的缩写韦氏儿童智力量表第三版口头和全面智商分数,视觉运动整合和运动协调标准化分数,和Bruininks-Oseretsky精细运动综合评分。回归分析表明,生物学母亲的词汇和家庭环境评估在同一个7年的访问是更强的预测发展的结果比产前药物暴露。可卡因暴露水平,但是,预测视觉运动和运动技能。结果表明,虽然产前可卡因暴露可能会赋予一定程度的视觉运动领域的发展劣势,它经常发生在一个不充分的养育环境,这可能是一个更强的决定因素比产前可卡因暴露儿童的结果。
Data are equivocal regarding the long-term consequences of prenatal exposure to cocaine on school-aged children. We compared 101 children exposed prenatally to cocaine with 130 unexposed children on measures of intelligence, visual motor, and motor abilities at age 7 years. Bivariate analyses revealed that cocaine-exposed children scored significantly lower than comparison children on the abbreviated Wechsler Intelligence Scale for Children-Third Edition Verbal and Full Scale IQ scores, the Visual Motor Integration and Motor Coordination standardized scores, and the Bruininks-Oseretsky Fine Motor Composite score. Regression analyses indicated that the biological mother's vocabulary and home environment assessed at the same 7-year visit were stronger predictors of developmental outcome than prenatal drug exposure. Level of cocaine exposure, however, predicted visual motor and motor skills. The results indicate that although prenatal cocaine exposure may confer some degree of developmental disadvantage in the visual motor domain, it frequently occurs in the context of an inadequate rearing environment, which may be a stronger determinant than prenatal cocaine exposure of children's outcome.