Bacterial adhesion not inhibited by ion-releasing bioactive glass filler
Bacterial adhesion not inhibited by ion-releasing bioactive glass filler
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DOI：
10.1016/j.dental.2017.04.002
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发表时间：
2017-06-01
期刊：
影响因子：
5
通讯作者：
Van Meerbeek, Bart
中科院分区：
文献类型：
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作者：
Yoshihara, Kumiko;Nagaoka, Noriyuki;Van Meerbeek, Bart
Objective.生物活性玻璃和表面预反应玻璃离子（sPRG）填料由于离子释放而具有防龋性能。许多研究调查了潜在的防龋作用;很少有研究评估其表面稳定性和表面在酸性条件下发生的结构变化。检查了sPRG填充的（Beautifil II，Shofu）和常规玻璃填充的（Herculite XRV Ultra，Kerr）树脂基复合材料（RBC）以及常规玻璃离子粘固剂（GIC; Fuji IX GP Extra，GC）对酸侵蚀的表面抗性以及对细菌粘附和生物膜形成的表面接受性。将样本（n = 3）浸入蒸馏水或乳酸（pH 4.0）中3天。用光密度和SEM记录细菌生长和生物膜形成。在乳酸中浸泡3天后，sPRG填充的RBC的表面显示出多个孔，而对于常规RBC和GIC几乎没有观察到表面完整性的变化。细菌生长测量显示，没有材料抑制变形链球菌（p
Objective. Bioactive glasses and surface pre-reacted glass-ionomer (sPRG) filler possess cario-static properties owing to ion release. Many studies investigated potential cariostatic effects; few studies evaluated the surface stability and the structural changes their surfaces undergo in acidic conditions.Methods. The surface resistance against acid attack and the surface receptiveness for bacterial adhesion and biofilm formation of a sPRG-filled (Beautifil ll, Shofu) and conventional glass-filled (Herculite XRV Ultra, Kerr) resin-based composite (RBC), and a conventional glass-ionomer cement (GIC; Fuji IX GP Extra, GC) were examined. Specimens (n = 3) were immersed in distilled water or lactic acid (pH 4.0) for 3 days. Bacterial growth and biofilm formation were recorded using optical density and SEM.Results. Upon 3-day immersion in lactic acid, the surface of the sPRG-filled RBC revealed multiple holes, while virtually no change in surface integrity was observed for the conventional RBC and GIC. Bacterial growth measurements revealed that none of the materials inhibited Streptococcus mutans (p