Horizontal gene transfer is not a hallmark of the human genome.
Horizontal gene transfer is not a hallmark of the human genome.
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DOI：
10.1186/s13059-017-1214-2
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发表时间：
2017-05-08
期刊：
影响因子：
12.3
通讯作者：
Salzberg SL
中科院分区：
文献类型：
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作者：
Salzberg SL
Crisp等人最近报道，145个人类基因已经从遥远的物种水平转移。在这里，我重新分析了Crisp等人列出的那些具有最高确定性的水平转移基因，以及2001年人类基因组文章中的17个基因，发现很少或没有证据支持水平基因转移（HGT）的说法。请参阅相关研究文章：https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0607-3本文的在线版本（doi：10.1186/s13059-017-1214-2）包含补充材料，可供授权用户使用。
Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as having the highest certainty of having been horizontally transferred, as well as 17 further genes from the 2001 human genome article, and find little or no evidence to support claims of horizontal gene transfer (HGT). Please see related Research article: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0607-3 The online version of this article (doi:10.1186/s13059-017-1214-2) contains supplementary material, which is available to authorized users.