Na+‐Dependent d‐Glucose Transport in Brush‐Border Membrane Vesicles of Chick Small Intestine: Relation to Na+/H+ Exchange and H+ Permeability a
Na+‐Dependent d‐Glucose Transport in Brush‐Border Membrane Vesicles of Chick Small Intestine: Relation to Na+/H+ Exchange and H+ Permeability a
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鸡小肠刷状缘膜囊泡中 Na+ 依赖性 d-葡萄糖转运：与 Na+/H+ 交换和 H+ 渗透性的关系
DOI：
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发表时间：
1985
影响因子：
5.2
通讯作者：
M. Peterlik
中科院分区：
文献类型：
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作者：
R. Fuchs;Jürg Graf;M. Peterlik
细胞质膜中Na + / H +交换已被证明部分地决定跨膜Na+和H +梯度，从而调节依赖于这些梯度的许多细胞功能。在鸡小肠刷状缘膜中，Na+梯度支持无机磷酸盐、D-葡萄糖和氨基酸的饱和转运，维生素D刺激无机磷酸盐、D-葡萄糖和氨基酸的饱和转运，维生素D也抑制Na + / H +交换。本研究考察了D-葡萄糖转运对跨膜Na+和H+梯度的依赖性。
N a + / H + exchange in cell plasma membranes has been shown to partially determine transmembrane Na+ and H + gradients and thus to regulate many cell functions dependent on these gradients. In chick intestine brush-border membrane, saturable transport of inorganic phosphate, D-glucose, and amino acids is supported by the N a + gradient and stimulated by vitamin D, which also inhibits N a + / H + exchange.’ This study examines the dependence of D-glucose transport on transmembrane N a + and H+ gradients.