Acute ataxia, Graves' disease, and stiff person syndrome
Acute ataxia, Graves' disease, and stiff person syndrome
复制标题
DOI：
10.1002/mds.21703
复制
发表时间：
2007-10-15
影响因子：
8.6
通讯作者：
Tan, Eng-King
中科院分区：
文献类型：
--
作者：
Chia, Su-Ynn;Chua, Richard;Tan, Eng-King
僵直人综合征（SPS）与自身免疫性疾病有关，如1型糖尿病和自身免疫性甲状腺疾病（桥本甲状腺炎）等。SPS与甲状腺功能亢进症的关联是非常罕见的。我们描述了一个病人与不受控制的格雷夫斯病和未确诊的SPS，谁提出了最初与急性共济失调模拟脑血管意外。免疫抑制治疗的开始在2周内显著改善了患者的Graves病，但在3年的随访期后，神经系统症状并未减轻。(C)2007年，《社会运动》创刊。
Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years. (C) 2007 Movement Disorder Society.