Studies using immobilized platelet glycoproteins for detection of platelet alloantibodies.
Studies using immobilized platelet glycoproteins for detection of platelet alloantibodies.
复制标题
使用固定化血小板糖蛋白检测血小板同种抗体的研究。
DOI:
10.1093/ajcp/104.3.258
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发表时间:
1995
影响因子:
3.5
通讯作者:
Kickler,TS
中科院分区:
文献类型:
--
作者:
Kim,HO;Kennedy,SD;Kickler,TS
The utility of an enzyme linked immunoassay for the detection of platelet alloantibodies to isolated platelet glycoproteins employing commercially available monoclonal antibodies was studied. The authors established the usefulness of the assay for antibodies to platelet alloantigens (APAA) by testing its sensitivity and specificity under different conditions and using a variety of alloantibodies from patients with immune mediated thrombocytopenia. The authors were able to specifically detect a variety of antibodies to platelet alloantigens on different platelet glycoproteins. These antibodies had specificity for HPA-la (PIAI), HPA-3 (Bak) and HPA-5 (Br).These results show that the APAA is easily adaptable for routine diagnostic testing in hospital laboratories using commercially available monoclonal antibodies and for the diagnosis of alloimmune mediated thrombocytopenic conditions.
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影响因子:
20.3
作者:
R. Mcmillan;P. Tani;F. Millard;P. Berchtold;Renshaw Lw;V. Woods
通讯作者:
R. Mcmillan;P. Tani;F. Millard;P. Berchtold;Renshaw Lw;V. Woods
DOI:
10.1172/jci113250
发表时间:
1987
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Furihata,K;Nugent,DJ;Bissonette,A;Aster,RH;Kunicki,TJ
通讯作者:
Kunicki,TJ
影响因子:
20.3
作者:
Bray,PF;Jin,Y;Kickler,T
通讯作者:
Kickler,T
DOI:
--
发表时间:
1990
期刊:
影响因子:
--
作者:
A. Borne;F. Décary
通讯作者:
F. Décary
影响因子:
20.3
作者:
TS Kickler;P. Ness;J. Herman;W. Bell
通讯作者:
W. Bell