Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant.

Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant.
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DOI:
10.1002/iju5.12499
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发表时间:
2022-09
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影响因子:
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通讯作者:
Miyazawa, Katsuhito
Miyazawa, Katsuhito
中科院分区:
其他
文献类型:
--
作者:
Inoue, Shinya;Shioya, Akihiro;Kunii, Kenshirou;Suga, Kodai;Morita, Nobuyo;Chikazawa, Ippei;Tanaka, Tatsuro;Miyazawa, Katsuhito

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一般来说,癌症患者禁忌肾移植,需要一定的随访期。我们报告一例晚期复发的肾细胞癌的患者谁接受了同时根治性肾切除术和尸体肾移植,由于肾细胞癌在肾移植12年后观察。一例48岁男性患者在肾移植过程中发现偶发性肾细胞癌,随后接受了同期尸体肾移植和根治性肾切除术。移植后12年,他患上了前纵隔肿瘤,肺肿瘤被切除,右肾上腺肿块与右肾一起被沿着切除。目前,由于左肾上腺转移,他正在接受酪氨酸激酶抑制剂治疗。对于接受肾移植的转移癌患者,应仔细考虑手术指征和免疫抑制剂的选择。
Generally, renal transplantation is contraindicated in cancer patients, and a certain follow‐up period is required. We report a case of late recurrence of renal cell carcinoma in a patient who underwent simultaneous radical nephrectomy and cadaver renal transplantation due to renal cell carcinoma observed during renal transplantation after 12 years. Incidental renal cell carcinoma was found in a 48‐year‐old man during kidney transplantation who subsequently underwent simultaneous cadaver kidney transplantation and radical nephrectomy. Twelve years after transplantation, he developed an anterior mediastinal tumor, a lung tumor which was resected and a right adrenal gland mass which was resected along with the right kidney. Currently, he is being treated with tyrosine kinase inhibitors owing to the metastasis in the left adrenal gland. In patients with metastatic carcinoma undergoing renal transplant, the indications for surgical procedures and choice of immunosuppressants should be carefully considered.