Electrophysiologic properties of the adult human sinus node
Electrophysiologic properties of the adult human sinus node
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DOI：
10.1111/j.1540-8167.1997.tb00788.x
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发表时间：
1997-03-01
影响因子：
2.7
通讯作者：
Drouin, E
中科院分区：
文献类型：
--
作者：
Drouin, E
人类 SA 结的电生理学。窦房结 (SA) 的电生理特性已在不同物种中进行了广泛的研究，已发表的关于人类 SA 结特性的研究是在胎儿 SA 结制剂上进行的；然而，成人心脏组织的电生理特性从未被检查过。在这项研究中，我们首次报告了成人窦房结跨膜电位的记录。我们的数据表明，成人窦房结起搏细胞的电行为与不同动物物种的窦房结组织相似。我们得出结论，后者理想地模仿了前者。此外，人窦房结制剂可能有助于更好地了解一些窦性心律失常。
Electrophysiology of the Human SA Node. Electrophysiologic properties of the sinoatrial (SA) node have been studied extensively in various species, Published studies on human SA nodal properties were carried out on fetal SA node preparations; however, the electrophysiologic properties of adult human cardiac tissues have never been examined, Tn this study we report, for the first time, recordings of transmembrane potentials in the adult human SA node, Our data demonstrate that the electrical behavior of adult human SA node pacemaker cells resemble those of SA nodal tissue of different animal species, We conclude that the latter ideally mimic the former, Furthermore, human SA node preparations could contribute to a better understanding of some sinus arrhythmias.