Insight into regulatory factor targeting to transcriptionally active subnuclear sites.
Insight into regulatory factor targeting to transcriptionally active subnuclear sites.
复制标题
深入了解针对转录活性亚核位点的调节因子。
DOI:
10.1006/excr.1999.4680
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发表时间:
1999
期刊:
影响因子:
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通讯作者:
Pockwinse,SM
中科院分区:
文献类型:
--
作者:
Stein,GS;vanWijnen,AJ;Stein,JL;Lian,JB;Javed,A;McNeil,S;Pockwinse,SM
Mechanisms that coordinate the spatial organization of genes and regulatory proteins within the three-dimensional context of nuclear architecture contribute to the sorting of regulatory information as well as the assembly and activity of sites within the nucleus that support gene expression. In this article we will present an overview of experimental approaches that provide insight into the trafficking of the hematopoietic and bone-specific AML/CBF family of regulatory factors to transcriptionally active subnuclear sites.