EEG source localization constrained by time varying fMRI.
EEG source localization constrained by time varying fMRI.
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脑电图源定位受时变功能磁共振成像的限制。
DOI：
10.1109/embc.2015.7318441
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
YingchunZhang
中科院分区：
文献类型：
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作者：
ThinhNguyen;Potter,Tom;Karmonik,Christof;Grossman,Robert;YingchunZhang
提出了一种新的脑电（EEG）和功能磁共振成像（fMRI）整合分析方法，用于探索“序列多事件相关电位”类型神经活动的空间和时间细节。该方法利用EEG的高时间分辨率性质来计算皮质活动的电流密度映射，由高空间分辨率fMRI以时变的、空间选择性的方式通知。该方法在对诱发情绪反应的视觉刺激的运动激活的EEG/fMRI研究的分析中实施。对处理后的加窗EEG信号进行分析，以选择时间相关的部分fMRI映射，这反过来又用于通知EEG源定位计算。结果与传统的fMRI知情的EEG方法进行了比较，以证明时空变化的fMRI约束功能以及所开发的方法的性能。
A novel approach for Electroencephalogram (EEG) and functional Magnetic Resonance Imaging (fMRI) integration analysis was developed, specifically designed to explore the spatial and temporal details of the “sequential multi-event-related potential” type of neural activities. The approach utilizes the high temporal resolution nature of EEG to compute a current density mapping of the cortical activity, informed by the high spatial resolution fMRI in a time-variant, spatially selective manner. This method was implemented in the analysis of an EEG/fMRI study on motor activation in responses to a visual stimulus that evoked an emotional response. The processed windowed EEG signals were analyzed to select the temporally relevant partial fMRI mapping, which in turn was used to inform EEG source localization calculation. The results were compared against traditional fMRI-informed EEG approaches to demonstrate the spatiotemporal variant fMRI constraints feature as well as the performance of the developed method.