Apoptosis as the mechanism of the involution of hair follicles in catagen transformation.
Apoptosis as the mechanism of the involution of hair follicles in catagen transformation.
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细胞凋亡是退行期转化中毛囊退化的机制。
DOI：
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发表时间：
1981
影响因子：
3.6
通讯作者：
G. Strutton
中科院分区：
文献类型：
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作者：
D. Weedon;G. Strutton
用电镜观察小鼠皮肤毛囊退化期的自发性退化过程。卵泡大小的减少似乎是由于细胞凋亡导致的细胞缺失，这是一种在组织动力学中具有重要意义的独特类型的细胞死亡。这些超微结构的变化在过去被误解为自噬空泡的形成，因为相邻的毛囊存活细胞对凋亡片段的显著吞噬作用。
Electron microscopy was performed on mouse skin to study the mechanism of the spontaneous involution of hair follicles during catagen. The reduction in follicles size appears to result from cell deletion by apoptosis, a distinct type of cell death with importance in tissue kinetics. These ultrastructural changes have been misinterpreted in the past as autophagic vacuole formation because of the prominent phagocytosis of the apoptotic fragments by adjacent, surviving cells of the hair follicle.