Non-spatial, motor-specific activation in posterior parietal cortex
Non-spatial, motor-specific activation in posterior parietal cortex
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DOI：
10.1038/nn862
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发表时间：
2002-06-01
影响因子：
25
通讯作者：
Snyder, LH
中科院分区：
文献类型：
--
作者：
Calton, JL;Dickinson, AR;Snyder, LH
猕猴后顶叶皮质中的一个局部神经元簇，被称为顶叶到达区(PRR)，在计划到达可见或记忆的目标时被激活。为了探索PRR在感觉运动转化中的作用，我们测试了当到达一个尚未明确的目标时，细胞是否会被激活。超过三分之一的PRR细胞在准备触觉的指令后增加了它们的放电，但在运动的目标仍然未知的情况下，不是在准备扫视的指令之后。当猴子被告知目标位置而不是要进行的运动类型时，部分重叠的种群(三分之二的细胞)被激活。因此，PRR神经元的子集分别编码空间和效应器特定的信息，这与指定对特定目标的潜在运动反应的作用一致。
A localized cluster of neurons in macaque posterior parietal cortex, termed the parietal reach region (PRR), is activated when a reach is planned to a visible or remembered target. To explore the role of PRR in sensorimotor transformations, we tested whether cells would be activated when a reach is planned to an as-yet unspecified goal. Over one-third of PRR cells increased their firing after an instruction to prepare a reach, but not after an instruction to prepare a saccade, when the target of the movement remained unknown. A partially overlapping population (two-thirds of cells) was activated when the monkey was informed of the target location but not the type of movement to be made. Thus a subset of PRR neurons separately code spatial and effector-specific information, consistent with a role in specifying potential motor responses to particular targets.