Wear Scar Similarities between Retrieved and Simulator-Tested Polyethylene TKR Components: An Artificial Neural Network Approach.

Wear Scar Similarities between Retrieved and Simulator-Tested Polyethylene TKR Components: An Artificial Neural Network Approach.
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DOI:
10.1155/2016/2071945
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发表时间:
2016
影响因子:
--
通讯作者:
Wimmer MA
Wimmer MA
中科院分区:
生物学3区
文献类型:
--
作者:
Orozco Villaseñor DA;Wimmer MA

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本研究的目的是确定模拟器测试的聚乙烯(PE)衬垫与从全膝关节置换术(TKR)中取出的聚乙烯衬垫的代表性磨损痕迹如何进行比较。通过非参数自组织特征图(SOFM),将21个尸检和54个翻修取出部件的磨痕图像与根据ISO协议在位移或载荷控制中进行测试的6个模拟器测试部件进行比较。然后使用死后取出部件的磨痕图像训练SOFM网络,因为这些图像在取出时被认为功能良好。基于这个训练过程中,建立了11个集群,这表明相当大的差异,尽管在其主机内的简单的加载历史的磨损疤痕。然后将剩余组件(修订版检索和模拟器测试)分配到这些已建立的集群中。五个模拟器组件中有六个聚集在一起,这表明网络能够识别加载历史中的相似性。然而,模拟器测试的组件最终在一个集群中的边缘的地图包含只有10.8%的检索组件。这可能表明,当前的ISO测试方案不能完全代表该TKR人群,并且可能需要更好地模拟患者在TKR后的步态(包含行走以外的活动)的方案。
The aim of this study was to determine how representative wear scars of simulator-tested polyethylene (PE) inserts compare with retrieved PE inserts from total knee replacement (TKR). By means of a nonparametric self-organizing feature map (SOFM), wear scar images of 21 postmortem- and 54 revision-retrieved components were compared with six simulator-tested components that were tested either in displacement or in load control according to ISO protocols. The SOFM network was then trained with the wear scar images of postmortem-retrieved components since those are considered well-functioning at the time of retrieval. Based on this training process, eleven clusters were established, suggesting considerable variability among wear scars despite an uncomplicated loading history inside their hosts. The remaining components (revision-retrieved and simulator-tested) were then assigned to these established clusters. Six out of five simulator components were clustered together, suggesting that the network was able to identify similarities in loading history. However, the simulator-tested components ended up in a cluster at the fringe of the map containing only 10.8% of retrieved components. This may suggest that current ISO testing protocols were not fully representative of this TKR population, and protocols that better resemble patients' gait after TKR containing activities other than walking may be warranted.
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