Effects of nosocomial candidemia on outcomes of critically ill patients
Effects of nosocomial candidemia on outcomes of critically ill patients
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DOI：
10.1016/s0002-9343(02)01248-2
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发表时间：
2002-10-15
影响因子：
5.9
通讯作者：
Colardyn, FA
中科院分区：
文献类型：
--
作者：
Blot, SI;Vandewoude, KH;Colardyn, FA
目的：确定院内念珠菌血症是否与重症监护病房 (ICU) 患者死亡率增加相关。 对象和方法：我们对 73 名 ICU 念珠菌血症患者和 146 名匹配对照者进行了一项回顾性（1992 年至 2000 年）队列研究。根据急性生理学和慢性健康评估 (APACHE) II 评分（+/- 1 分）衡量的疾病严重程度、诊断类别以及念珠菌血症发作前 ICU 住院时间来匹配对照组。 结果：与对照组相比，念珠菌血症患者在 ICU 住院期间发生更多急性呼吸衰竭（97% [n = 71] vs. 88% [n = 129]，P = 0.03）。他们接受较长时间的机械通气（29 +/- 26 天与 19 +/- 19 天，P
PURPOSE: To determine whether nosocomial candidemia is associated with increased mortality in intensive care unit (ICU) patients.SUBJECTS AND METHODS: We performed a retrospective (1992 to 2000) cohort study of 73 ICU patients with candidemia and 146 matched controls. Controls were matched based on disease severity as measured by the Acute Physiology and Chronic Health Evaluation (APACHE) II score (+/- 1 point), diagnostic category, and length of ICU stay before onset of candidemia.RESULTS: In comparison with the control group, patients with candidemia developed more acute respiratory failure (97% [n = 71] vs. 88% [n = 129], P = 0.03) during their ICU stay. They were mechanically ventilated for a longer period (29 +/- 26 days vs. 19 +/- 19 days, P