Asthma and air pollution in the Los Angeles area.
Asthma and air pollution in the Los Angeles area.
复制标题
洛杉矶地区的哮喘和空气污染。
DOI：
10.2105/ajph.70.7.687
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发表时间：
1980
影响因子：
12.7
通讯作者：
E. Korn
中科院分区：
文献类型：
--
作者：
A. Whittemore;E. Korn
环境保护局收集了 1972 年至 1975 年期间 34 周期间居住在洛杉矶地区的 16 名哮喘患者的每日哮喘发作日记。这里检查了每日攻击发生率与每日光化学氧化剂水平、总悬浮颗粒物、最低温度、相对湿度和平均风速之间的关系。每个小组成员的攻击数据都使用单独的多重逻辑回归。代表前一天是否存在攻击、以及自研究开始以来一周中的哪一天和时间的变量都包含在回归中。最重要的攻击预测因素是前一天是否发生攻击。平均而言，小组成员在高氧化剂和颗粒物污染的日子、凉爽的日子以及研究的前两个月期间的攻击次数往往会增加。小组成员的攻击倾向也因星期几而异。特别是周六（每周报告期的最后一天）发生的袭击比周日更多。每个小组成员的回归系数根据年龄、性别、花粉症状况和自我评估的攻击前兆进行分类；该分类用于检查小组成员中具有与上述因素相对应的高系数的子组。
Daily asthma attack diaries of 16 panels of asthmatics residing in the Los Angeles area were collected by the Environmental Protection Agency for 34-week periods during the years 1972-1975. There data are examined here for the relationship between daily attack occurrence and daily levels of photochemical oxidant, total suspended particulates, minimum temperature, relative humidity, and average wind speed. A separate multiple logistic regression is used for each panelist's attack data. Variables representing the presence or absence of attack on the preceding day, as well as day of week and time since the start of the study, are included in the regressions. The most significant predictor of attacks was the presence of an attack on the preceding day. On the average, the panelists tended to have increased attacks on days with high oxidant and particulate pollution, on cool days, and during the first two months of the study. Panelists' attack propensity also differed by day of week; in particular they had more attacks on Saturdays (the last day of the weekly reporting period) than on Sundays. Each panelist's regression coefficients are classified according to age, sex, hay fever status, and self-assessed attack precursors; this classification is used to examine subgroups among the panelists with high coefficients corresponding to the above factors.