Impact of chronic prostatitis-like symptoms on the quality of life in a large group of men
Impact of chronic prostatitis-like symptoms on the quality of life in a large group of men
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DOI：
10.1111/j.1464-410x.2007.07250.x
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发表时间：
2007-12-01
影响因子：
4.5
通讯作者：
Karakiewicz, Pierre I.
中科院分区：
文献类型：
--
作者：
Walz, Jochen;Perrotte, Paul;Karakiewicz, Pierre I.
目的 使用美国国立卫生研究院慢性前列腺炎症状指数 (NIH-CPSI) 评估一大群男性中慢性前列腺炎 (CP) 和慢性盆腔疼痛综合征 (CPPS) 症状的患病率，并评估哪些 NIH-CPSI 症状对生活质量 (QoL) 影响最大。 对象和方法 NIH-CPSI 由 1273 名男性在一次男性健康促进活动中完成。 CP/CPPS 样症状的存在根据 NIH-CPSI 标准（会阴疼痛或射精疼痛且 NIH-CPSI 疼痛评分 >= 4）进行定义。最后，使用线性回归分析，我们评估了每个问卷症状对 NIH-CPSI-QoL 领域的影响。 结果 男性的平均（范围）年龄为 57.6（40-89）岁； 133 人 (10.5%) 报告有 CP/CPPS 样症状，其中 62 人 (4.9%) 报告有轻度 CP/CPPS 样症状，71 人 (5.6%) 报告有中度至重度 CP/CPPS 样症状。具有 CP/CPPS 样症状的男性具有较高的 NIH-CPSI-QoL 评分，显示出对 QoL 的更大损害（4.9 vs 2.5；P < 0.001）。在所有 NIH-CPSI 症状中，尿频与最差的生活质量相关，其次是膀胱排空不完全、疼痛频率和疼痛强度。个体疼痛部位对生活质量没有显着影响。结论在大量健康人群中，CP/CPPS 样症状很常见，对生活质量有重要影响。功能性 CP/CPPS 样症状对生活质量的不利影响比疼痛症状更大。因此，这些症状应该代表受影响患者的主要治疗目标。
Objective To assess the prevalence of chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) symptoms in a large group of men, using the National Institute of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), and to evaluate which of the NIH-CPSI symptoms had the most detrimental effect on quality of life (QoL).Subjects and methods The NIH-CPSI was completed by 1273 men during a male-health promotion event. The presence of CP/CPPS-like symptoms was defined according to the NIH-CPSI criteria (perineal pain or ejaculatory pain and NIH-CPSI-pain score >= 4). Finally, using linear regression analyses we evaluated the effect of each questionnaire symptom on the NIH-CPSI-QoL domain.Results The mean (range) age of the men was 57.6 (40-89) years; 133 (10.5%) reported CP/CPPS-like symptoms, with 62 (4.9%) reporting mild and 71 (5.6%) reporting moderate to severe CP/CPPS-like symptoms. Men with CP/CPPS-like symptoms had higher NIH-CPSI-QoL scores, showing a greater detriment of QoL (4.9 vs 2.5; P < 0.001). Of all NIH-CPSI symptoms, urinary frequency was associated with the least favourable QoL, followed by incomplete bladder emptying, pain frequency and pain intensity. The individual pain location had no significant impact on the QoL.Conclusion In a large healthy population CP/CPPS-like symptoms are common and have an important impact on QoL. Functional CP/CPPS-like symptoms have a greater detrimental effect on QoL than pain symptoms. Therefore, these symptoms should represent the main therapeutic targets in affected patients.