The course of anhedonia during 10 years of schizophrenic illness
The course of anhedonia during 10 years of schizophrenic illness
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DOI：
10.1037/0021-843x.111.2.237
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发表时间：
2002-05-01
影响因子：
4.6
通讯作者：
Harrow, M
中科院分区：
文献类型：
--
作者：
Herbener, ES;Harrow, M
尽管快感缺失被认为是精神分裂症患者的一种特质，但其持久性和稳定性尚未通过多年的多次评估进行测试。不同研究对快感缺乏的具体定义各不相同，不同类型快感缺乏之间的关系以及它们在病程中与精神分裂症症状的关系尚未得到解决。目前的研究使用前瞻性收集的纵向数据，涵盖 127 名精神分裂症患者，涵盖 10 年的时间跨度，发现 (a) 身体快感缺失是 10 年来的稳定特征，但不是抑郁性的； (b) 身体快感缺乏与精神病、消极或抑郁症状没有表现出强烈且一致的关系，并且 (c) 一些病前特征与身体快感缺乏之间的关系即使在病程 10 年后也很显着。
Although anhedonia has been proposed to be a trait-like characteristic in schizophrenia patients, its persistence and stability have not been tested using multiple assessments over a multiyear period. Specific definitions of anhedonia vary across studies, and relationships between different types of anhedonia as well as their relationship to schizophrenic symptoms over the course of illness have not been addressed. The current research, using prospectively collected longitudinal data covering a 10-year span for 127 individuals with schizophrenic illness, found that (a) physical, but not depressive, anhedonia is a stable characteristic over a 10-year period; (b) physical anhedonia does not show strong and consistent relationships with psychotic, negative, or depressive symptoms and (c) the relationship between some premorbid characteristics and physical anhedonia are significant even 10 years into the course of illness.