Hierarchical emergence of sequence sensitivity in the songbird auditory forebrain
Hierarchical emergence of sequence sensitivity in the songbird auditory forebrain
复制标题
鸣禽听觉前脑序列敏感性的分层出现
DOI：
10.1007/s00359-016-1070-7
复制
发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Y.
中科院分区：
文献类型：
--
作者：
Ono;S.;Okanoya;K.;& Seki;Y.
孟加拉雀(Lonchura striatavar.home tica)在歌声中比斑马雀产生更复杂的序列。正因为如此，我们选择了这种物种来探索声音序列在初级听觉前脑区L区域和次级区域中的尾内侧nidopalum(NCM)的信号处理。我们同时记录了乌拉坦麻醉鸟的多个单一单位的活动。我们成功地复制了之前在觉醒的斑马雀身上进行的一项研究的结果，该研究检查了NCM神经元对同种特定歌曲的刺激特定习惯化。然后，我们使用了一个古怪的范式，并将神经对不常见的异常声音的反应与对频繁出现的标准声音的反应进行了比较。在一项单一声音古怪任务中，两个不同的歌曲元素被分配给不同的声音和标准声音。在三重序列奇数任务中，两个含有ABC和ACB元素的三联体序列被指定为偏差和标准序列。只有NCM中呈现宽形棘波的神经元对元素顺序的不同敏感。我们的结果表明鸣禽听觉前脑中复杂声音序列的分层处理。
Bengalese finches (Lonchura striatavar.domestica) generate more complex sequences in their songs than zebra finches. Because of this, we chose this species to explore the signal processing of sound sequence in the primary auditory forebrain area, field L, and in a secondary area, the caudomedial nidopallium (NCM). We simultaneously recorded activity from multiple single units in urethane-anesthetized birds. We successfully replicated the results of a previous study in awake zebra finches examining stimulus-specific habituation of NCM neurons to conspecific songs. Then, we used an oddball paradigm and compared the neural response to deviant sounds that were presented infrequently, with the response to standard sounds, which were presented frequently. In a single sound oddball task, two different song elements were assigned for the deviant and standard sounds. The response bias to deviant elements was larger in NCM than in field L. In a triplet sequence oddball task, two triplet sequences containing elements ABC and ACB were assigned as the deviant and standard. Only neurons in NCM that displayed broad-shaped spike waveforms had sensitivity to the difference in element order. Our results suggest the hierarchical processing of complex sound sequences in the songbird auditory forebrain.