Transcranial direct current stimulation accelerates allocentric target detection.
Transcranial direct current stimulation accelerates allocentric target detection.
复制标题
经颅直流电刺激加速异中心目标检测。
DOI：
10.1016/j.brs.2012.05.008
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发表时间：
2013
影响因子：
7.7
通讯作者：
Hamilton,RoyH
中科院分区：
文献类型：
--
作者：
Medina,Jared;Beauvais,Jacques;Datta,Abhishek;Bikson,Marom;Coslett,HBranch;Hamilton,RoyH
研究背景以往关于半侧空间忽视的研究为自我中心和他中心加工的分离机制提供了证据。尽管一些研究已经检查了后顶叶皮质的tDCS是否有利于神经功能完整的个体的注意力处理，但没有一项研究检查了tDCS对非自我中心和/或自我中心处理的潜在影响。目的/假设我们的目的是检查是否经颅直流电刺激（tDCS），一种可以增加（阳极）或减少的无创脑刺激技术（阴极）皮层活动，可以影响视觉空间处理的allocentric和/或自我中心的参考框架。METHODS我们测试了健康的个人对目标检测任务，其中的目标-一个圆圈的差距-要么是右边或左边的观众（自我中心），或包含一个缺口的右侧或左侧的圆（allocentric）。个体在三种刺激条件之一--右阳极/左阴极、右阴极/左阳极和假刺激--的tDCS之前、期间和之后对后顶叶皮层执行任务。使得与右侧间隙相比，右侧阳极/左侧阴极tDCS导致用于检测具有左侧间隙的刺激的更快的反应时间。结论我们的研究表明，右阳极/左阴极tDCS有一个易化的影响allocentric视觉空间处理，并可能是有用的，作为一种治疗技术，为个人遭受allocentric忽视。
BACKGROUNDPrevious research on hemispatial neglect has provided evidence for dissociable mechanisms for egocentric and allocentric processing. Although a few studies have examined whether tDCS to posterior parietal cortex can be beneficial for attentional processing in neurologically intact individuals, none have examined the potential effect of tDCS on allocentric and/or egocentric processing.OBJECTIVE/HYPOTHESISOur objective was to examine whether transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique that can increase (anodal) or decrease (cathodal) cortical activity, can affect visuospatial processing in an allocentric and/or egocentric frame of reference.METHODSWe tested healthy individuals on a target detection task in which the target – a circle with a gap – was either to the right or left of the viewer (egocentric), or contained a gap on the right or left side of the circle (allocentric). Individuals performed the task before, during, and after tDCS to the posterior parietal cortex in one of three stimulation conditions – right anodal/left cathodal, right cathodal/left anodal, and sham.RESULTSWe found an allocentric hemispatial effect both during and after tDCS, such that right anodal/left cathodal tDCS resulted in faster reaction times for detecting stimuli with left-sided gaps compared to right-sided gaps.CONCLUSIONSOur study suggests that right anodal/left cathodal tDCS has a facilitatory effect on allocentric visuospatial processing, and might be useful as a therapeutic technique for individuals suffering from allocentric neglect.