Motion correction for functional MRI with three-dimensional hybrid radial-Cartesian EPI
Motion correction for functional MRI with three-dimensional hybrid radial-Cartesian EPI
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DOI：
10.1002/mrm.26390
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发表时间：
2017-08-01
影响因子：
3.3
通讯作者：
Miller, Karla L.
中科院分区：
文献类型：
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作者：
Graedel, Nadine N.;McNab, Jennifer A.;Miller, Karla L.
受检者运动是功能磁共振成像（fMRI）图像质量下降的主要原因之一，特别是在使用三维（3D EPI）等多激发序列时。我们提出了一个混合径向笛卡尔三维EPI轨迹，使运动校正在k空间的功能MRI.MethodsThe EPI叶片的三维混合径向笛卡尔EPI序列，称为涡轮机，旋转的相位编码轴，以填补了一个圆柱体在三维k空间。使用黄金角旋转增量随时间获取有角度叶片，从而允许以灵活的时间分辨率进行重建。该序列的自导航特性用于从高时间分辨率导航器时间序列确定运动参数。作为图像重建的一部分，在k空间中校正运动，结果我们证明，运动校正工作鲁棒性，我们可以实现大量的伪影减少，以及改善时间信噪比和fMRI激活的存在下，严重和微妙的运动。Cartesian 3D EPI可大幅减少fMRI应用中的伪影，特别是对于头部运动明显的受试者组。运动校正方法不会延长扫描时间，并且不需要额外的硬件。Magn Reson Med 78：527-540，2017年。(c)2016年《The Authors Magnetic Resonance in Medicine》由Wiley Periodicals，Inc.出版。国际医学磁共振学会（International Society for Magnetic Resonance in Medicine）这是一个开放获取的条款下的知识共享署名许可证，允许使用，分发和复制在任何媒体上，只要原始作品是适当的引用。
PurposeSubject motion is a major source of image degradation for functional MRI (fMRI), especially when using multishot sequences like three-dimensional (3D EPI). We present a hybrid radial-Cartesian 3D EPI trajectory enabling motion correction in k-space for functional MRI.MethodsThe EPI blades of the 3D hybrid radial-Cartesian EPI sequence, called TURBINE, are rotated about the phase-encoding axis to fill out a cylinder in 3D k-space. Angular blades are acquired over time using a golden-angle rotation increment, allowing reconstruction at flexible temporal resolution. The self-navigating properties of the sequence are used to determine motion parameters from a high temporal-resolution navigator time series. The motion is corrected in k-space as part of the image reconstruction, and evaluated for experiments with both cued and natural motion.ResultsWe demonstrate that the motion correction works robustly and that we can achieve substantial artifact reduction as well as improvement in temporal signal-to-noise ratio and fMRI activation in the presence of both severe and subtle motion.ConclusionWe show the potential for hybrid radial-Cartesian 3D EPI to substantially reduce artifacts for application in fMRI, especially for subject groups with significant head motion. The motion correction approach does not prolong the scan, and no extra hardware is required. Magn Reson Med 78:527-540, 2017. (c) 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.