CHANGING INCIDENCE OF BREAST-CANCER IN JAPANESE-AMERICAN WOMEN
CHANGING INCIDENCE OF BREAST-CANCER IN JAPANESE-AMERICAN WOMEN
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DOI：
10.1093/jnci/51.5.1479
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发表时间：
1973-01-01
期刊：
影响因子：
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通讯作者：
BUELL, P
中科院分区：
文献类型：
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作者：
BUELL, P
1950 ~ 1960年间的死亡率研究显示，日裔美国妇女的乳腺癌死亡率仅略高于日本的普遍水平，尽管其他特定部位的癌症风险已明显向白色美国人的水平转移。1969年至1971年的第三次全国癌症调查显示，旧金山-奥克兰大都市地区日裔美国妇女患乳腺癌的风险接近白人。这种向上的转变发生在第二代（Nisei）和第一代（Issei）之间。第一代的贡献是巨大的，但略低于第二代。虽然日本和波兰移民几乎同时抵达美国，而且都是农村移民，但到1950年，只有波兰妇女患乳腺癌的风险大幅增加。日本移民可能保留了他们的传统文化更长时间，当乳腺癌风险发生强烈上升时，在成年前和成年早期可能暴露于新文化和环境的日裔美国妇女中也是如此。
Mortality studies for the period around 1950 and 1960 showed breast cancer mortality rates of Japanese-American women only slightly above levels prevailing in Japan, though other site-specific cancer risks had shifted more markedly toward levels of white Americans. The Third National Cancer Survey of 1969–71 reveals that breast cancer risks for Japanese-American women in the San Francisco-Oakland metropolitan area closely approached those for whites. This upward shift occurred among both the Nisei (second generation) and the Issei (immigrant generation). The contribution of the Issei to the increased rates was substantial but somewhat less than that of the Nisei. Although Japanese and Polish migrants arrived in the United States about the same time, and both were mainly of rural origin, only the Polish women demonstrated a substantially increased risk of breast cancer by 1950. Japanese migrants may have retained their traditional culture longer, and when the strong upward shift in breast cancer risk occurred, it did so among Japanese-American women potentially exposed to a new culture and environment at preadult and early adult ages.